Wednesday, January 2, 2008

Fallopian Tube Cancer Staging

The following is adapted from the Federation of Gynecology and Obstetrics ( FIGO) staging system for fallopian tube carcinoma.

Stage 0 Carcinoma in situ (limited to tubal mucosa)

Stage I Growth limited to the fallopian tubes

Stage IA Growth limited to one tube with extension into submucosa and/or muscularis but not penetrating the serosal surface, no ascites

Stage IB Growth limited to both tubes with extension into submucosa and/or muscularis but not penetrating the serosal surface, no ascites

Stage 1C Tumor either stage 1A or 1B with tumor extension through or onto the tubal serosa OR with ascites containing malignant cells OR with positive peritoneal washings

Stage II Growth involving one or both fallopian tubes with pelvic extension

Stage IIA Extension and/or metastasis to the uterus and/or ovaries

Stage IIB Extension to other pelvic tissues

Stage IIC Tumor either stage IIA or IIB AND with ascites containing malignant cells OR with positive peritoneal washing.

Stage III Tumor involving one or both fallopian tubes with peritoneal implants outside of the pelvis and/or positive retroperitoneal or inguinal nodes. Superficial liver metastases equals stage III. Tumor seems limited to the true pelvis with negative nodes but with histologically proved malignant extension to the small bowel or omentum

Stage IIIA Tumor grossly limited to the true pelvis with negative nodes but with histologically confirmed microscopic seeding of abdominal peritoneal surfaces

Stage IIIB Tumor involving one or both tubes with histologically confirmed implants of abdominal peritoneal surfaces, none exceeding 2 cm in diameter. Lymph nodes negative

Stage IIIC Abdominal implants greater than 2 cm in diameter and/or positive retroperitoneal or inguinal nodes

Stage IV Growth invading one or both fallopian tubes with distant metastases. If pleural effusion is present, there must be positive cytology to be stage IV. Parenchymal liver metastases equal stage IV